Main page
Syllabus
Overview
Grades
Schedule
Assignments
Messages
Resources

Chemistry 519: Biochemistry and Molecular Biology
Spring Semester 2017
Professor Peter Qin
LJS 251
Tel: : (213) 821-2461
pzq@usc.edu

 

Lecture Schedule: Updated January 22, 2017

Week Date Topic
Week 1 Jan. 09 Class Introduction
Lecture notes #1
  Jan. 11 Review of Basic Chemical & Physical Concepts
Lecture notes #2
  Jan. 13 Amino Acid & Peptides
Lecture notes #3
Week 2 Jan. 16 University Holiday
  Jan. 18 Protein Structure
Lecture notes #4
  Jan. 20 Protein Folding
Lecture notes #5
Week 3 Jan. 23 Protein mis-folding
Lecture notes #6
  Jan. 25 Nucleotide
Lecture notes #7
  Jan. 27 DNA duplex structure
Lecture notes #8
Week 4 Jan. 30 DNA melting & stability
Lecture notes #9
  Feb. 01 RNA; RNA structure
Lecture notes #10
  Feb. 03 Enzymatic synthesis: transcription, translation; DNA replication
Lecture notes #11
Week 5 Feb. 06 No Class
  Feb. 08 Chemical Synthesis of Peptides
Lecture notes #12
  Feb. 10
Molecular Biology Techniques
Lecture notes #13
Week 6 Feb. 13 Chemical Synthesis of DNA/RNA
Lecture notes #14
  Feb. 15
PCR; DNA sequencing
Lecture notes #15
  Feb. 17 Basic Enzymology
Lecture notes #16
Week 7 Feb. 20 [University Holiday]
  Feb. 22 Basic Enzymology: M-M mechanism [HW1 due]
Lecture notes #17
  Feb. 24 Basic Enzymology: inhibition; Midterm review
Lecture notes #18
Week 8 Feb. 27 Enzyme regulation: Cooperativity
Lecture notes #19
  Mar. 01 Midterm (closed book; lectures 01/11 -- 02/15)
  Mar. 03 Enzyme; catalytic strategy; Protease & Nuclease
Lecture notes #20
Week 9 Mar. 06 Nucleases; catalytic strategy
Lecture notes #21
  Mar. 08 Ribozymes; small ribozyme
Lecture notes #22
  Mar. 10 Ribozymes; large ribozyme
Lecture notes #23
March 12 - 19 Spring Break
Week 10 Mar. 20 History of gene editing
Lecture notes #24
  Mar. 22 gene editing with ZFN; protein-DNA recognition
Lecture notes #25
  Mar. 24 protein-DNA recognition: TALEN & gene editing
Lecture notes #26
Week 11 Mar. 27 CRISPR-Cas: general background
Lecture notes #27
  Mar. 29 The Type II CRISPR-Cas9: background
Lecture notes #28
  Mar. 31 Stauffer Symposium
Week 12 Apr. 03 Cas9: applications in gene editing and control
Lecture notes #29
  Apr. 05 Cas9: structure and mechanism
Lecture notes #30
  Apr. 07 Cas9: structure and mechanism
Lecture notes #31
Week 13 Apr. 10 Cas9 mechanism; Engineering of Cas9
Lecture notes #32
  Apr. 12 Cas9 Engineering
Lecture notes #33
  Apr. 14 Other CRISPR
Lecture notes #34
Week 14 Apr. 17 SELEX and in vitro evolution
Lecture notes #35
  Apr. 19 SELEX and in vitro evolution
Lecture notes #36
  Apr. 21 Oral presentations
Week 15 Apr. 24 Oral presentations
  Apr. 26 Oral presentations
  Apr. 28 Oral presentations; Review
2nd half review
Final May. 08 Final exam; 9 - 10 am; Closed Book

 

© 2010, Chemistry Dept.,  University of Southern California